Top 22 Best Over the Counter Benzoyl Peroxide Acne Products – Ultimate Review & Guide

Benzoyl peroxide has been clincially proven to be one of the most effective treatments for acne. They come in different strengths (2.5%, 5%, 10%) many forms from face washes and cleaners to creams, lotions, and gels.

The Best Benzoyl Peroxide Acne Products – Ultimate Review & Guide

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The Benefits of Benzyol Peroxide for Treating Acne

Benzoyl peroxide has been proven to be effective in preventing and treating inflammatory (cysts, red pimples, and zits) and non-inflammatory (blackheads and whiteheads) acne.[1]

It has major acne-fighting actions:

  1. It’s a very effective anti-bacterial agent – by releasing free radical oxygen, which is lethal to the p. acne bacteria, and benzoic acid, which prevents further infection.[2]
  2. It has anti-inflammatory and comedolytic effects – it resolves and prevents the formation of new comedones (blackheads and whiteheads).
  3. It’s a lipophilic (oil-loving) exfoliant – most products are water-soluble and can only affect the skin’s surface (remember oil and water don’t mix). Benzoyl peroxide is capable of diving into an oil-filled pore and clears it of clogs and sebum. This is what makes it an effective face wash as well.
  4. It can promote wound healing – by attracting macrophages and histiocytes (types of white blood cells that protect the body from infection) into the wound.[3]

It comes in varying strengths (2.5–20%) and can be found as face wash/cleansers or as leave-on creams, gels, and lotions

Video: What is Benzoyl Peroxide? by Dr. Neal Schultz, MD

Ask the Expert: How to Use Benzoyl Peroxide to Treat Acne

by Samantha Welch, Esthetician

  1. It’s important to acclimatize or let your skin adjust when introducing any new product, especially if you have sensitive skin. Your safest bet is to start with the lowest % strength, using it twice a week. Gradually increase usage to once daily or as needed as you go on. You can work you way up in % or frequency when you feel like your skin needs and is prepared for it. If any dryness or peeling occurs, reduce the frequency or % strength.
  2. If used in the daytime, always complement with a non-comedogenic sunscreen. BP can cause photosensitivity in some, which makes your skin particularly vulnerable to sun damage.
  3. For best results, do not use hydroquinone and benzoyl peroxide at the same time. Hydroquinone is a brightening/whitening ingredient. You can check the label of your other products if you’re not sure.
  4. Lastly, just because I can’t emphasize it’s importance enough, always follow up with an effective, non comedogenic moisturizer. This is a very, very crucial step — after applying a benzoyl peroxide product, let is absorb for a few minutes and follow up with a gentle and deeply hydrating moisturizer. 

Moisturizing is truly not optional if you want to have clear and healthy skin. We want the benefits of benzoyl peroxide, not any of its side-effects.

Be sure to find a moisturizer and a hydrating toner that is gentle and won’t irritate your skin (opt for formulations for sensitive skin).

Also, check that it is lightweight and non-comedogenic so as to not further aggravate your acne. BP has also shown to penetrate more effectively on a well-hydrated skin.

Related: The Best Non-Comedogenic Moisturizers for Oily Skin; The Best Non-Comedogenic Moisturizers for Acne-Prone Skin


Benzoyl Peroxide Creams, Gels, Lotions, & Ointments

  1. Use a gentle cleanser before application. Follow up with a hydrating toner (without alcohol or astringent) to prep the skin.
  2. On a clean, slightly damp skin; apply on the affected area either as a spot treatment or an all-over lotion. Quick tip: A slightly damp skin is more permeable that skin that’s completely dried.
  3. Follow-up with a hypoallergenic and non-comedogenic moisturizer right after. This is to prevent excessive drying or irritation and restore skin balance. Some of the higher end brands have formulations that already contain moisturizing ingredients to calm and soothe the skin, but you will still need to double down on the hydration to help keep your skin balanced.

Benzoyl Peroxide Face & Body Wash

  1. Massage gently on the skin for at least 20 seconds.
  2. Follow with a hypoallergenic and non-comedogenic moisturizer.
Table Of Contents
  1. The Benefits of Benzyol Peroxide for Treating Acne
  2. Ask the Expert: How to Use Benzoyl Peroxide to Treat Acne
  3. Ask the Expert: Choosing the Right Type of Benzoyl Peroxide Product for You
  4. Level 1: 2.5% Benzoyl Peroxide Products
  5. Ask the Expert: Skincare Routine Tips
  6. Level 2: 5% Benzoyl Peroxide Products
  7. Ask the Expert: What are the Potential Side-Effects of Benzoyl Peroxide?
  8. Level 3: 10% Benzoyl Peroxide Products
  9. Esthetician's Choice: The Best Benzoyl Peroxide Moisturizers, Lotions, Creams, & Gel
  10. Esthetician's Choice: The Best Benzoyl Peroxide Face Washes & Cleansers
  11. Recommended Acne Programs
  12. Frequently Asked Questions
  13. References:
  14. Top 22 Best Over the Counter Benzoyl Peroxide Acne Products – Ultimate Review & Guide
  15. Recommended Acne Programs

Ask the Expert:
Choosing the Right Type of Benzoyl Peroxide Product for You

by Samantha Welch, Esthetician

At first glance, leave-on acne products seem to be more effective as they stay on the skin longer.

However, efficacy is still down to the strength of the product, how well it’s formulated, and how receptive your skin is to it.

When choosing a product, you’ll need to consider the following:

  • You need to assess your skin’s current condition to determine the strength %. (Is your skin resistant enough for a 5%? 10%?)
  • With reference to leave-on product’s thickness and consistency; gels are usually the most lightweight and preferred by oily skin, followed by lotions and creams. This is not a hard and fast rule, however. Some lotions can be formulated to be more absorbent than gels. Creams are commonly thick and used for dry or dehydrated skin.
  • Another very important factor is your lifestyle and preference. One of the main reasons why people go off a skin regime is because they think of it as a chore. You should be able to enjoy the experience and the product itself to an extent so you’re able to use it on a regular basis.

Below are our selection of the best over the counter benzoyl peroxide products in the market today.

Esthetician's Choice:
The Best Over the Counter Benzoyl Peroxide Products

We’ve arranged the product listing below in ascending order, based on medication strength.

If you’re new to BP, you can start with a 2.5% and work your way up. Your choice of formulation, i.e. face wash, cream, lotion, etc. depends on your preference and current skincare routine.

Take the list for a spin and remember, choose products that are most compatible with your skin type and needs.


Level 1: 2.5% Benzoyl Peroxide Products

When used as a topical treatment ie. creams, lotions, gels, etc.; always start with the lowest concentration to allow your skin to adapt to the medication. A 2.5% strength is effective in most cases of moderate acne.[4]

This is one of the key steps that most people easily overlook, which causes the misconception that the product isn’t working whereas it was just used incorrectly.

Use a small amount once a day, every other day for the first two weeks, and gradually increase the dosage in the succeeding weeks. You’ll then need to observe your skin for any stinging or severe redness. This usually means you need to step back lower either the dosage or frequency of use.

Paula’s Choice – Clear Acne Treatment Regular Strength Lotion (2.5% Benzoyl Peroxide for Moderate Acne)

Best for: All skin types, Mild to moderate acne; Reducing redness, Controlling excess oil, Hydrating to minimize dryness

Our Review:

Paula’s Choice specializes in correcting skin concerns including acne, rosacea, and skin aging. The brand prides itself in having non-irritating formulations that are also clinically effective. All their products are 100% fragrance-free, colorant-free, and cruelty-free.

This ultra-light lotion is part of their CLEAR line aimed toward acne-prone skin at any age. It combines 2.5% benzoyl peroxide with soothing plant extracts to help minimize skin peeling and dryness. That said, I still find this moderately drying so I would recommend using this in conjunction with a hydrating moisturizer.

You can use it as a daily spot treatment on inflamed acne, as well as over areas where you usually break out as a preventive measure.

This is oil-free and sets to a soft, invisible, matte finish; perfect for wear under makeup especially for those with oily skin.

Also available in 5% strength for more severe breakouts.

Best for: All skin types and ages struggling with mild to moderate acne; Oily skin, Under makeup


Dr. Song Acne Gel Treatment Lotion​ (2.5% Benzoyl Peroxide)

Dr. Song Acne Gel Treatment Lotion​ (2.5% Benzoyl Peroxide)

Best for: All skin types; Resistant, Acne-prone skin

Our Review:

If you’re looking for a simple and affordable BP treatment; this one’s for you. For the price of a fairly large bottle, it comes in at a much better value than even drugstore staples. They also have a 100-day money back, hassle-free guarantee for any issues.

This gel lotion has minimal ingredients which help reduce possible sensitivities or allergies. However, since it’s quite a simple formulation, it also comes with all the side effects of BP. You’ll need to have resistant (i.e. not sensitive) and hydrated skin to assist in making the product work for u. Make sure to also ready your moisturizer to manage the dryness and irritation.

Overall, a simple and great value alternative to the drugstore and high-end BP treatments.

Best for: All skin types; Resistant, Acne-prone skin


Acne.org 16 oz. Treatment (2.5% Benzoyl Peroxide)

Acne.org 16 oz. Treatment (2.5% Benzoyl Peroxide)

Best for: All skin types; Overall face treatment

Our Review:

One of the few that is used not just as a spot treatment, but all over the face. It is step 2 of Acne.org’s famous 3-Step System. Below is a video from the developer himself on how to apply the treatment. Recommended if you have constant breakouts in large areas.

This benzoyl peroxide is pharmaceutical-grade and triple milled so it penetrates the skin better than regular formulations. The gel base absorbs quickly and goes on smoothly without clumping with other moisturizers. It also doesn’t turn white when you perspire.

This size should last for 2-4 months on The Acne.org Regimen.

Pharmaceutical grade, pH balanced, fragrance-free, and dye-free.

Best for: All skin types, overall face treatment

Video Review:

Video: Applying Acne.org Benzoyl Peroxide on The Acne.org Regimen


GlyMed Plus Serious Action Skin Wash

GlyMed Plus Serious Action Skin Wash

Best for: Unbalanced and Inflammed Acne-Prone skin

Our Review:

This cleanser blends the anti-acne power of benzoyl peroxide and the soothing, anti-inflammatory properties of aloe vera.

This combination helps restore the skin’s healthy balance that would otherwise be extremely thrown off by BP. Aloe vera is one of the oldest medicinal plants known and has the same pH as human skin so it’s extremely healing and protective.

It doesn’t do deep cleaning though, so if you have oily skin; you might be better off with a cleanser that doubles as an exfoliant. If you have normal skin that’s prone to breakouts, this should be right up your alley.

Best for: Unbalanced and problematic Acne-Prone skin; looking for an extra soothing, anti-inflammatory BP cleanser


Acnefree Oil Free Acne Cleanser

Acnefree Oil Free Acne Cleanser

Best for: All skin types, Acne-prone skin

Our Review:

This product has been reformulated a while back. It now has a better texture, no more menthol, a bit thinner, and no more beads.

It also has a patented continuous-relief micronized benzoyl peroxide. This means that the molecules of the BP are smaller than average, making absorption faster and going in deeper to treat acne. This feature is usually found in the more high-end lines so I’m a bit surprised that it’s in a more affordable brand.

It claims to reduce sebum but I can’t see anything in the ingredients or formulation that specifically addresses oil control so I’d take this with a grain of salt.

Overall, it is their continuous-relief micronized benzoyl peroxide that makes it stand out among its peers. If you’re looking for a more effective and affordable BP cleanser, you can’t go wrong with Acnefree. (Don’t forget to moisturize after! This can be super drying and irritating.)

Best for: All skin types with Acne-prone skin; looking for an affordable 2.5% benzoyl peroxide face wash


Proactiv+ Skin Smoothing Exfoliator

Proactiv+ Skin Smoothing Exfoliator

Best for: All skin typess; Resistant, Acne-prone skin with Dull, Uneven texture

Our Review:

This daily face wash is a 4-in-1 multi-functional marvel that comes in an airy and cushiony cream. It works as: a deep cleanser, a benzoyl peroxide medication, a glycolic-acid toner, and a mild exfoliator. Surprisingly, it doesn’t contain the usual irritators that come with most multi-purpose cleansers. This has hardly any fragrance.

Exfoliation is done two-fold: both physical and chemical for a thorough deep clean. Glycolic acid works to loosen any dead skin cells so the tiny exfoliating beads can gently slough them off. This helps unclog pores and helps renew the skin for a smoother texture and healthier complexion. The 2.5% benzoyl peroxide is exclusively micro-crystalized for deeper penetration.

The dual exfoliation comes as double-edged. This means the potential for over-exfoliation for sensitive skins is two-fold as well. If you’re giving this a try, make sure not to scrub too hard to avoid this.

Non-greasy, Sulfate-free, Paraben-free, Non-comedogenic.

Best for: All skin types; Resistant, Acne-prone skin with dull, uneven texture


Vivant Skin Care – Benzoyl Peroxide 3% Exfoliating Cleanser, 8 Ounce

Vivant Skin Care – Benzoyl Peroxide 3% Exfoliating Cleanser

Best for: Combination to Oily skin, Blemish-prone skin with large pores & prone to scarring

Our Review:

A little bump up in concentration at 3%, but not too far off.

It has all-natural, renewable, and biodegradable cellulose buffing beads to help deep clean and flush out any impacted debris in the skin. It also helps refine pores and accelerate cell renewal to clear out acne with minimal scarring.

Non-comedogenic, Cruelty-free.

Best for: Combination to Oily skinAcne-prone skin with large pores and prone to scarring

Ask the Expert: 
Skincare Routine Tips

Ask the Expert:
Skincare Routine Tips

by Samantha Welch, Esthetician

Use a gentle cleanser followed by a hydrating toner before application to avoid dryness and irritation.

After application, use a hypoallergenic, non-comedogenic moisturizer to counter the side effects and restore the skin’s pH.

Benzoyl Peroxide also penetrates more effectively on well-hydrated skin.

Level 2: 5% Benzoyl Peroxide Products

If the 2.5 formulation is no longer cutting it and you feel like you can opt for a stronger concentration, you can step up to 5%. After going through 2.5%, your skin should have acclimated to the medication, making it safe for you to use this daily.

This works best on large, inflamed cystic acne.

There was a study that showed a significant reduction in the p. acne bacteria after only 2 days of application of a 5% BP gel, with a clinical improvement as early as 4 days. Take this as a possible outcome if you have the right product that works well for your skin condition. You can also use this in conjunction with an antibacterial like clindamycin.[5, 6]

If you can also avoid picking on the bump, it should eventually flatten and not leave any physical scarring.

Glytone Acne 3P Treatment Gel

Glytone Acne 3P Treatment Gel

Best for: All skin types; Dehydrated oily or dry skin; Spot treatments, Under make-up

Our Review:

This physician-only product line holds some of the most popular and well-known exfoliating skin care. Glytone is a staple in clinics worldwide because of its innovative and customized approach to formulating with the highest free acid values (i.e., unlike other brands, their acids are not compounds or diluted down).

Glytone in-office treatments are usually prescribed with at-home regimens to work synergistically. This maximizes product efficacy and skin tolerability, giving you visible, long-lasting results.

This treatment gel is part of Glytone’s Acne Clearing Set. It has a patented time-released micronized benzoyl peroxide, which means the product is able to mimic the body’s physiological dosage. This gives it a more natural rhythm and makes the skin more receptive to it. This type of delivery system ensures maximum absorption while minimizing potential irritation.

Its innovative hydro-gel formulation hydrates the skin and fends off dryness while continually fighting acne throughout the day.

Non-whitening matte finish. Non-irritating formula. Fragrance-free. Oil-free. Non-comedogenic.

Best for: All skin types especially dehydrated oily or dry skin; looking for spot treatments, those who don’t have exfoliating products in their regimen; under make-up


PCA SKIN Acne Cream

PCA SKIN Acne Cream

Best for: All skin types; Spot treatments

Our Review:

The spot treatment version of the PCA SKIN BPO 5% Cleanser.

Instead of phytic acid, however, the exfoliant that comes with the cream is lactic acid. This is the gentlest type of AHA among all the alpha-hydroxy acids and is the most moisturizing.

It also has tea tree oil in the mix, one of the most established botanicals that heal acne and promotes a clear complexion.

Best for: All skin types; looking for spot treatments, those who don’t have exfoliating products in their regimen.


La Roche-Posay Effaclar Duo Acne Treatment with 5.5% Benzoyl Peroxide

La Roche-Posay Effaclar Duo Acne Treatment with 5.5% Benzoyl Peroxide

Best for: Spot treatments, Acne blemishes, Blackheads, Whiteheads

Our Review:

This is step #3 of the award-winning Effaclar Dermatological Acne System by La Roche-Posay. This acne spot treatment uses 5.5% micronized benzoyl peroxide and their micro-exfoliating lipo-hydroxy acid (LHA).

It helps clear whiteheads, blackheads, and reduces the severity of acne blemishes.

Results can be seen as fast as 3 days and have been proven to reduce acne by 60% in 10 days.

Dermatologist-tested. Paraben-free. Fragrance-free. Oil-free.

Awards:

  • 2017 The Knot Beauty Awards: Face
  • 2017 InStyle Best Beauty Buys
  • 2017 Teen Vogue Online Acne Awards/Spot Treatment – Benzoyl Peroxide
  • 2015 InStyle Best Beauty Buys
  • 2015 Nylon Best Spot Treatment
  • 2014 InStyleBest Beauty Buys
  • 2014 Nylon Beauty Hit List
  • 2012 All You Best Beauty Buys
  • 2012 Nylon Beauty Hit List: Best Acne Aid

Best for: Acne spot treatments


Glo Skin Beauty Therapeutics Clear Anti-Blemish Treatment

Glo Skin Beauty Therapeutics Clear Anti-Blemish Treatment

Best for: All skin types, Skin prone to redness and irritation

Our Review:

Use as a spot treatment for current breakouts and to prevent future flare-ups. It disappears into the skin and can be used under makeup.

Along with a good dose of acne-fighting 5% benzoyl peroxide, it has aloe vera and rosemary to help prevent reduce inflammation and redness. These also help in the healing and repairing of skin that was damaged by acne. Glycerin is added as well and works in tandem with aloe vera for added hydration.

If you have skin that’s prone to redness, you can start with a small amount and use it every other day to let your skin adjust. Make sure to follow up with a good moisturizer as well.

Best for: All skin types, skin prone to redness and irritation


M.A.D Skincare Blemish Repelling Gel Benzoyl Peroxide 5%

M.A.D Skincare Blemish Repelling Gel Benzoyl Peroxide 5%

Best for: Oily and Combination skin

Our Review:

A non-drying, lightweight gel-cream that absorbs quickly into the skin. It delivers a potent blend of benzoyl peroxide, licorice, green tea, and Epilobium Fleischeri extract.

Epilobium Fleischeri extract is an innovative ingredient that is very effective to reduce sebum on oily skin. It also reduces inflammation and the appearance of pores. Great for the T-zone and areas you need to minimize pores.

Green tea and licorice have antioxidant properties to help keep your skin looking and feeling younger.

No parabens or chemical colorants.

Best for: Oily and Combination skin


PCA SKIN BPO 5% Cleanser

PCA SKIN BPO 5% Cleanser

Best for: Existing acne lesions

Our Review:

PCA is a brand known for its corrective and potent formulations using alpha-hydroxy acids. Exfoliants improve the health and appearance of skin by promoting cell renewal and preventing the buildup of dead skin cells.

This daily cleanser has a unique combination of 5% benzoyl peroxide and phytic acid (exfoliant) to eliminate existing and prevent future breakouts.

Gluconolactone is a calming, moisturizing ingredient that promotes a clear complexion. Botanical extracts soothe irritated and inflamed blemishes, allowing the skin to heal.

Free of potential irritants like synthetic dyes and fragrances. PCA SKIN® does not perform or condone animal testing.

Best for: All skin types; looking for face treatments, those who don’t have exfoliating products in their regimen


Replenix Acne Solutions Benzoyl Peroxide Wash 5% / 10%

Replenix Acne Solutions Benzoyl Peroxide Wash 5% / 10%

Best for: Normal & Oily Skin, Acne-Prone skin

Our Review:

This face wash is fortified with the highest USP grade benzoyl peroxide to provide a potent antibacterial effect against acne. Replenix’s Acne Solutions line uses pharmaceutical-grade and micronized benzoyl peroxide to effectively penetrate the skin without leaving any residue.

This was developed for dermatology clinics and as a safe and affordable solution for pediatric, adolescent, and adult patients. It can be used together with topical or oral antibiotics to help reduce the risk of bacterial resistance.

This cleanser is also gentle enough without drying or irritating normal skin and can be used up to twice daily for full efficacy.

Paraben-free. Gluten, Oil, and Fragrance-free. Soap-free.
Non-comedogenic (will not clog pores). Hypoallergenic.

Available in 5% and 10% strength.

Best for: Normal & Oily Skin, Acne-Prone skin


Beauty Facial Extreme – Benzoyl Peroxide 5% Acne Cleanser for Face & Body

Beauty Facial Extreme – Benzoyl Peroxide 5% Acne Cleanser for Face & Body

Best for: Acne-prone skin on the face, body, and back

Our Review:

USP grade BPO wash that’s clinically proven to be non-irritating and safe for all skin types.

It’s formulated for use on the face and body, perfect if you also have acne on the back or other parts. Using BP daily can help not only in fighting current breakouts but also prevent acne bacteria from building up before they start.

It comes in a big bottle with a dispensing pump for convenience in the shower. Very creamy and lathers pretty well.

Paraben-free and Fragrance-free. Cruelty-free and not tested on animals. 30-Day Money Back Guarantee.

Also available in 10% benzoyl peroxide formulation.

Best for: Acne-prone skin on the face, body, and back; looking for a BP face wash with a convenient pump


5% Benzoyl Peroxide Face Wash by Harris Pharmaceuticals

5% Benzoyl Peroxide Face Wash by Harris Pharmaceuticals

Best for: Looking for a drugstore BP facial wash

Our Review:

This is the most popular ‘generic’ BP facial wash, with good reviews across the board.

I can’t quite get a hold of the ingredients from the manufacturer, but I did get a list from one of their distributors. It’s essentially a cleanser formulation + 5% BP. Pretty straightforward, so it should hold up to standard if you don’t have particular sensitivities or allergies. Just always make sure to follow up with a great moisturizer because this will very likely dry your skin without it.

Best for: If you have resistant skin and you’re looking for an affordable solution without the bells and whistles, you can give this one a go.

Also available in 10% strength.

Ask the Expert:
What are the Potential Side-Effects of Benzoyl Peroxide?

by Samantha Welch, Esthetician


Before including this in your regimen, however, you need to be aware of its possible side effects including:

  1. Extreme skin dryness – If you use it as a spot treatment, the skin surrounding the spot will start to flake off. If you use it all over the face, your skin can start to crack and peel off in blotches (Sounds scary, I know! But stay with me here)
  2. Redness and skin irritation

Now for the catch-22: dry skin can clog pores and irritated skin practically guarantees breakouts in acne-prone skin.

The solution?

Use a gentle cleanser before application and after, a non-comedogenic moisturizer to counter the side effects and restore the skin’s pH.

Level 3: 10% Benzoyl Peroxide Products

The 10% concentration is the strongest you can get without a prescription.

A study has shown that after applying 10% BP for two weeks, the p. acnes bacteria on the skin have decreased as much as 98% and oil on the skin has reduced by 50%. These results are similar to taking four weeks of antibiotics.

Move onto this if you have consistent, inflamed acne or would like to keep breakouts at bay.

Jan Marini Skin Research Benzoyl Peroxide Acne Treatment Lotion 10%

Jan Marini Skin Research Benzoyl Peroxide Acne Treatment Lotion 10%

Best for: Normal to Oily Skin

Our Review:

Jan Marini Skin Research (JMSR) is one of the world’s leading professional skincare brands, carried by physicians worldwide. They are known for their award-winning and innovative formulas.

This product is quite unique as the benzoyl peroxide in this lotion is highly micronized and combined with specialized emollients (moisturizers). This ensures maximum delivery of your 10% BP (which is also the max % you’ll be able to get OTC, so max 2x!) while minimizing its side effects of dryness and irritation.

To use, cover the affected area starting every other day to 1-3x daily.

Also available in 5% strength.

Best for: Normal to Oily Skin


Jan Marini Skin Research Age Intervention Duality – 10% BP

Jan Marini Skin Research Age Intervention Duality – 10% BP

Best for: Adult acne on all skin types

Our Review:

For severe breakouts, this treatment cream by Jan Marini addresses even the most stubborn adult acne. It contains ultra-micronized benzoyl peroxide, highly concentrated all-trans-retinol, green tea extract, and advanced hydratorsAnti-aging peptides and antioxidants minimize the appearance of fine lines and wrinkles in the process.

In a 3-month independent physician study, 100% of subjects experienced a reduction in acne lesion count. Continuous improvements we seen through its 4-week completion.

Best for: Adult acne on all skin types


10% Generic for Oxy-10 Balance Acne Treatment Medication Maximum Strength Gel

10% Generic for Oxy-10 Balance Acne Treatment Medication Maximum Strength Gel

Best for: Looking for a drugstore spot-on gel

Our Review:

Oxy-10 was previously a prescription topical medication for acne.

This is a very strong, straight-up BP leave-on gel. This means that you’ll have to do due diligence in dealing with the side effects that come with using benzoyl peroxide like dryness, redness, and irritation.

The good news is, that you can pretty much cover this with a good hydrating and non-comedogenic moisturizer. Look for one that has extra calming and soothing ingredients.

The consistency is a little thicker than the usual gel but it still dries quickly and shouldn’t slide off even in your sleep.

The package comes with several tubes which should last you a very long time.

Active Ingredient: 10% Benzoyl Peroxide

Best for: All skin types, Resistant skin, Affordable alternative


Dermatologic Cosmetic Laboratories B Prox Anti-Blemish Face Wash

Dermatologic Cosmetic Laboratories B Prox Anti-Blemish Face Wash

Best for: All skin types especially oily skin with large pores

Our Review:

DCL’s anti-acne formulation is a multi-tasker that aims to eliminate the cause, reduce the side effects, and prevent acne from coming back.

The 10% BP washes away acne-causing bacteria, while its detoxifying mineral-rich clay and plant extracts work to absorb excess oil and refine pore size. This helps prevent any future breakouts–a critical feature if you have oily skin.

It also has an Advanced Algae Complex that helps diminish the sensitivity that often accompanies the use of aggressive acne treatments, and Canadian Willow Herb to help visibly and dramatically reduce redness and soothe irritation.

All in all, a power-packed product for those who would like their BP treatment done to the next level.

Dermatologist tested. Paraben-free. Non-comedogenic, hypoallergenic. 

Best for: All skin types especially oily skin with large pores


PanOxyl Acne Foaming 10% Benzoyl Peroxide Face Wash

PanOxyl Acne Foaming 10% Benzoyl Peroxide Face Wash

Best for: Normal, resistant skin

Our Review:

Another dermatologically prescribed product, this foaming wash would work well for normal skin.

Looking at the formulation though, there are a number of potential irritants present. If you have sensitivities or allergies to certain cleansers, I would stay clear of this one. It can also be drying, so always follow up with a very hydrating moisturizer.

Best for: Normal, resistant skin. If you’re looking for an affordable, standard BP face wash; this PanOxyl foaming wash may be the right fit for you.


Humane Benzoyl Peroxide 10% Acne Treatment Body & Face Wash

Humane Benzoyl Peroxide 10% Acne Treatment Body & Face Wash

Best for: Acne-prone skin on the face, body, and back

Our Review:

The only brand amongst all mentioned having an EWG rating. This means that it is environmentally friendly, there are no harmful chemicals used, and there is a very low chance of irritation or allergic reactions to any of their line.

Highest EWG safety rating of 1. No parabens, SLS, fragrance, or animal testing. 100% hassle-free guarantee.

Best for: Acne-prone skin on the face, body, and back

Recommended Acne Programs


If you're suffering from severe acne, it's best to undergo a program that will help you get to the root of the problem and address the causes. 

Esthetician's Choice:
The Best Benzoyl Peroxide Moisturizers, Lotions, Creams, & Gel

Brand / Product Name:Product Image:Benzoyl Peroxide Strength:Added Benefits:Best for (Skin Type & Condition):
Paulas Choice Clear Acne Treatment Regular Strength Lotion with 2.5% Benzoyl Peroxide for Moderate AcnePaula’s Choice - Clear Acne Treatment Regular Strength Lotion (2.5% Benzoyl Peroxide for Moderate Acne)2.5%Soothing plant extracts (minimize skin peeling & dryness). Sets to a soft, invisible, matte finish.All skin types, Mild to moderate acneRead Review
2.5% Benzoyl Peroxide Dr. Song Acne Gel Treatment LotionDr. Song Acne Gel Treatment Lotion​ (2.5% Benzoyl Peroxide)2.5%Simple, affordable benzoyl peroxide lotion. 100-day money back guarantee.All skin types. Resistant skin.Read Review
Acne.org 16 oz. Treatment (2.5% Benzoyl Peroxide)Acne.org 16 oz. Treatment (2.5% Benzoyl Peroxide)2.5%Pharmaceutical-grade & triple milled for extra penetration. Preventive acne treatment.All skin types. For overall face treatment.Read Review
Glytone Acne 3P Treatment GelGlytone Acne 3P Treatment Gel5%Patented time-released micronized benzoyl peroxide. Non-whitening matte finish.All skin types especially dehydrated, oily or dry skin.Read Review
PCA SKIN Acne CreamPCA SKIN Acne Cream5%Lactic acid (gentle exfoliation). Tea tree oil (antibacterial).All skin types especially those prone to dry patches.Read Review
M.A.D Skincare Blemish Repelling Gel Benzoyl Peroxide 5%M.A.D Skincare Blemish Repelling Gel Benzoyl Peroxide 5%5%Green tea, licorice (antioxidant). Epilobium Fleischeri extract (oil control, pore minimizing).Oily to Combination skin.Read Review
Glo Skin Beauty Clear Skin Spot Treatment – Acne & Pimple Spot TreatmentGlo Skin Beauty Therapeutics Clear Anti-Blemish Treatment5%Aloe vera & Rosemary (anti-inflammatory, antioxidant). Glycerin (hydration).All skin types especially those prone to redness & inflammation.Read Review
La Roche-Posay Effaclar Duo Acne Treatment with 5.5% Benzoyl PeroxideLa Roche-Posay Effaclar Duo Acne Treatment with 5.5% Benzoyl Peroxide5.5%Multi-award-winning Effaclar Dermatological Acne System. 5.5% micronized BP with micro-exfoliating lipo-hydroxy acid (LHA), proven to reduce acne by 60% in 10 days.Spot treatments of acne blemishes, blackheads, & whiteheads.Read Review
Jan Marini Skin Research Benzoyl Peroxide Acne Treatment Lotion 10%Jan Marini Skin Research Benzoyl Peroxide Acne Treatment Lotion 10%10%Highly micronized BP combined with specialized emollients for maximum delivery & minimum side effects.Normal to Oily Skin.Read Review
Jan Marini Skin Research Age Intervention Duality – 10% BPJan Marini Skin Research Age Intervention Duality – 10% BP10%Ultra-micronized benzoyl peroxide, highly concentrated all-trans-retinol, green tea extract, advanced hydrators, anti-aging peptides and antioxidants.Medium to severe Adult Acne on all skin types.Read Review
10% Generic for Oxy-10 Balance Acne Treatment Medication Maximum Strength Gel10% Generic for Oxy-10 Balance Acne Treatment Medication Maximum Strength Gel10%All skin types. Resistant skin.Oily skin with open and large pores on cheeks, nose, forehead, and chin; Combination skin with oily T-zones.Read Review

Esthetician's Choice:
The Best Benzoyl Peroxide Face Washes & Cleansers

Brand / Product Name:Product Image:Benzoyl Peroxide Strength:Additional Benefits:Best for (Skin Type & Condition):
GlyMed Plus Serious Action Skin WashGlyMed Plus Serious Action Skin Wash2.5%Soothing, anti-inflammatory properties of aloe vera.Unbalanced and problematic Acne-Prone skin.Read Review
Acnefree Oil-Free Acne CleanserAcnefree Oil Free Acne Cleanser2.5%Patented continuous-relief micronized benzoyl peroxide.All skin types; Acne-prone skin.Read Review
Proactiv+ Skin Smoothing ExfoliatorProactiv+ Skin Smoothing Exfoliator2.5%4-in-1 multi-functional daily face wash with glycolic acid and exfoliating beads. Non-greasy, sulfate-free, paraben-free, non-comedogenic.All skin types; Resistant, Acne-prone skin with dull, uneven texture.Read Review
Vivant Skin Care – Benzoyl Peroxide 3% Exfoliating Cleanser, 8 OunceVivant Skin Care – Benzoyl Peroxide 3% Exfoliating Cleanser, 8 Ounce3%All natural, renewable, and biodegradable cellulose buffing beads. Non-comedogenic, cruelty-free.Combination to Oily skin; Acne-prone skin with large pores and prone to scarring.Read Review
PCA SKIN BPO 5% CleanserPCA SKIN BPO 5% Cleanser5%Benzoyl peroxide + phytic acid (exfoliant). Moisturizing, soothing botanical extracts. No synthetic dyes, cruelty-free.All skin types; Resistant, Acne-prone skin with dull, uneven texture.Read Review
Replenix Acne Solutions Benzoyl Peroxide WashReplenix Acne Solutions Benzoyl Peroxide Wash 5% / 10%5%, 10%Formulated for dermatologists. Contains USP grade, micronized benzoyl peroxide for potency and efficacy in penetrating the skin.Acne-prone skin, Normal to Oily Skin.Read Review
Beauty Facial Extreme – Benzoyl Peroxide 5% Acne Cleanser for Face & BodyBeauty Facial Extreme – Benzoyl Peroxide 5% Acne Cleanser for Face & Body5%, 10%Formulated for face & body. Paraben-free, fragrance-free, cruelty free.Combination skin with large pores and fine linesRead Review
5% Benzoyl Peroxide Face Wash by Harris Pharmaceuticals5% Benzoyl Peroxide Face Wash by Harris Pharmaceuticals5%, 10%Simple, affordable benzoyl peroxide face wash.Normal, resistant, acne-prone skin.Read Review
Dermatologic Cosmetic Laboratories B Prox Anti-Blemish Face WashDermatologic Cosmetic Laboratories B Prox Anti-Blemish Face Wash
10%
Detoxifying mineral-rich clay to absorb excess oil and refine pore size. Plant extracts to reduce sensitivity and soothe redness & irritation. Dermatologist tested. Paraben-free. Non-comedogenic, hypoallergenic.(Very) Oily, Acne-prone skin with large pores.Read Review
PanOxyl Acne Foaming 10% Benzoyl Peroxide Face WashPanOxyl Acne Foaming 10% Benzoyl Peroxide Face Wash
10%
Simple, affordable benzoyl peroxide face wash.Normal, resistant, acne-prone skin.Read Review
Humane Benzoyl Peroxide 10% Acne Treatment Body & Face WashHumane Benzoyl Peroxide 10% Acne Treatment Body & Face Wash
10%
Highest EWG safety rating of 1. No parabens, SLS, fragrance, or animal testing; Formulated for face & body.Formulated for face & body; Acne-prone skin on the face, body, and back.Read Review

Recommended Acne Programs


If you're suffering from severe acne, it's best to undergo a program that will help you get to the root of the problem and address the causes. 

Frequently Asked Questions


References:

  1. Kawashima, M., Nagare, T. and Katsuramaki, T. (2017), Open-label, randomized, multicenter, phase III study to evaluate the safety and efficacy of benzoyl peroxide gel in long-term use in patients with acne vulgaris: A secondary publication. J Dermatol, 44: 635-643. https://doi.org/10.1111/1346-8138.13741
  2. Matt Sagransky, Brad A Yentzer & Steven R Feldman (2009) Benzoyl peroxide: a review of its current use in the treatment of acne vulgaris, Expert Opinion on Pharmacotherapy, 10:15, 2555-2562, DOI: 10.1517/14656560903277228
  3. Alvarez OM, Mertz PM, Eaglstein WH. Benzoyl Peroxide and Epidermal Wound Healing. Arch Dermatol. 1983;119(3):222–225. doi:10.1001/archderm.1983.01650270040014
  4. Stein Gold, L., Weiss, J., Rueda, M.J. et al. Moderate and Severe Inflammatory Acne Vulgaris Effectively Treated with Single-Agent Therapy by a New Fixed-Dose Combination Adapalene 0.3 %/Benzoyl Peroxide 2.5 % Gel: A Randomized, Double-Blind, Parallel-Group, Controlled Study. Am J Clin Dermatol 17, 293–303 (2016). https://doi.org/10.1007/s40257-016-0178-4
  5. Kawashima, M., Sato, S., Furukawa, F., Matsunaga, K., Akamatsu, H., Igarashi, A., Tsunemi, Y., Hayashi, N., Yamamoto, Y., Nagare, T. and Katsuramaki, T. (2017), Twelve-week, multicenter, placebo-controlled, randomized, double-blind, parallel-group, comparative phase II/III study of benzoyl peroxide gel in patients with acne vulgaris: A secondary publication. J Dermatol, 44: 774-782. https://doi.org/10.1111/1346-8138.13798

Top 22 Best Over the Counter Benzoyl Peroxide Acne Products – Ultimate Review & Guide

Benzoyl peroxide has been clinically proven to be one of the most effective treatments for acne. They come in different strengths (2.5%, 5%, 10%) many forms from face washes and cleaners to creams, lotions, and gels.

Samantha Welch

The Best Benzoyl Peroxide Acne Products – Ultimate Review & Guide

Summary

We’ve arranged the product listing in ascending order, based on medication strength. It comes in varying strengths (2.5–20%) and can be found as face wash/cleansers or as leave-on creams, gels, and lotions. 

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Samantha Welch
Samantha Welch is an esthetician and professional makeup artist. She co-founded Healthy Beautiful to create a space where she can share her experiences and channel her love for all things beauty. Samantha believes that through education and resources, everyone can make informed choices that can change their lives.