The Best Benzoyl Peroxide Creams, Gels, & Lotions for Acne Spot Treatments – Most mild to moderate cases of acne can be treated effectively with drugstore cleansers and ointments.
The strongest and most effective over the counter acne treatments contain benzoyl peroxide.
- 1 Editor’s Choice: The Best Benzoyl Peroxide Creams, Gels, & Lotions
- 1.1 Paula's Choice Clear Acne Treatment Regular Strength Lotion with 2.5% Benzoyl Peroxide for Moderate Acne
- 1.2 2.5% Benzoyl Peroxide Dr. Song Acne Gel Treatment Lotion
- 1.3 Acne.org 16 oz. Treatment (2.5% Benzoyl Peroxide)
- 1.4 Glytone Acne 3P Treatment Gel
- 1.5 PCA SKIN Acne Cream
- 1.6 Glo Skin Beauty Therapeutics Clear Anti-Blemish Treatment
- 1.7 M.A.D Skincare Blemish Repelling Gel Benzoyl Peroxide 5%
- 1.8 Jan Marini Skin Research Benzoyl Peroxide Acne Treatment Lotion 10%
- 1.9 10% Generic for Oxy-10 Balance Acne Treatment Medication Maximum Strength Gel
How Does Benzoyl Peroxide Work?
Benzoyl peroxide works to both prevent and treat inflammatory acne (cysts, red pimples, and zits) and non-inflammatory (blackheads and whiteheads).
It has 3 major acne-fighting actions:
- It’s a very effective exfoliant – it clears pores of clogged oils and dead skin which are the root causes of blackheads and whiteheads. This exfoliation action also expedites cell turnover, which helps heal the spot.
- It’s anti-bacterial – by releasing oxygen, which is lethal to the p. acne bacteria.
- It promotes wound healing – by attracting macrophages and histiocytes (types of white blood cells that protects the body from infection) into the wound.
How to Use Benzoyl Peroxide for Acne:
Before including this in your regimen, you need to be aware of its possible side effects. This is crucial because expecting these and knowing how to deal with it head on is one of the keys of a successful treatment.
Possible side effects include:
- Extreme skin dryness – If your skin is sensitive or isn’t resistant enough, it can start to crack and peel off in blotches (Sounds scary, I know! But stay with me here)
- Redness and skin irritation, bit of stinging if you have extra sensitive skin
Now for the catch-22: dry skin can clog pores and irritated skin practically guarantees breakouts in acne-prone skin.
Use a hypoallergenic, non-comedogenic moisturizer after application to counter the side effects and restore the skin’s pH.
Be sure to find a moisturizer that is gentle and won’t irritate your skin (opt for formulations for sensitive skin). Also check that it is lightweight and non-comedogenic so as to not further aggravate your acne.
If used in daytime, complement with a broad spectrum sunscreen.
Important Notes: It’s also important to acclimatize or let your skin adjust when incorporating any new product. Your safest bet is to start with the lowest % strength, using it once every other day. Gradually increase usage to 2-3 times daily or as needed as you go on. You can work you way up in % or frequency when you feel like your skin needs and is prepared for it. If any dryness or peeling occurs, reduce the frequency or % strength.
For best results, do not use hydroquinone and benzoyl peroxide at the same time. (It’s a brightening/whitening ingredient. You can check the label of your other products if you’re not sure.)
You also need to set your expectations when using over the counter products like these. I’ve had acne since my teens until well into my twenties and have tried almost every acne product I can get my hands on in hopes of finding that miracle product that will end my suffering. (I know this sounds overly dramatic but when you’ve had acne for more than a decade, ‘suffering’ and ‘agony’ really isn’t an exaggeration. 🙁 )
Benzoyl peroxide has been very effective for me but it is by no means a cure-all. If you’re suffering from persistent acne, its best to undergo a program that will help you get to the root of the problem and address the causes. Acclaimed programs like Mike Walden’s Acne No More and Clear Skin Unlocked can be a great start.
Video: What is Benzoyl Peroxide? by Dr. Schultz, MD
Our recommendations for the best creams and other topical treatments with benzoyl peroxide are based on our comprehensive analysis of the product’s formulation, claims, value for money, and consumer reviews. We make an effort to be as objective as possible and give advice in good faith; however, our reviews may still contain conjectures and opinions based on our research and personal experiences.
It’s important to know that as with any product (especially cosmetics), what may be perfect for you may not be right for the next person. So as much as we want to guarantee that these will be everyone’s next holy grail, results can still be affected by individual factors like your current skin condition, the environment you’re in, use of the product, reaction to your other skincare, and so on. For best results, make sure to choose a product that is suited for your skin type and skin issues.
This website is for informational purposes and is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
Product or service details are collected directly from the manufacturer and other reputable sources during the time of this review. Extended research and studies are cited in the Resources section. We try to keep on top of new formulations when we can, and update our data accordingly.
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Editor’s Choice: The Best Benzoyl Peroxide Creams, Gels, & Lotions
These are our choices for the best topical treatments with benzoyl peroxide based on formulation, our experience, value for money, specifications, and consumer reviews over the years.
Make sure to choose one that is most suited for your skin type and condition.
Video: Applying Acne.org Benzoyl Peroxide on The Acne.org Regimen
Adapalene/benzoyl peroxide clearly superior in facial acne. (2007). Inpharma Weekly, &NA;(1617), p.14.
Alvarez, O. (1983). Benzoyl peroxide and epidermal wound healing. Archives of Dermatology, 119(3), pp.222-225.
Cohen, H. (1975). Benzoyl Peroxide Gel in Acne Treatment. Archives of Dermatology, 111(11), p.1535.
Colman, G. and Roenigk, H. (1978). The Healing of Wounds in the Skin of Piglets Treated with Benzoyl Peroxide. The Journal of Dermatologic Surgery and Oncology, 4(9), pp.705-707.
Del Rosso, J. and Zeichner, J. (2016). Advances in Acne Management, An Issue of Dermatologic Clinics. 1st ed. Saintt Louis: Elsevier Health Sciences.
Evidence for the Use of a Benzoyl Peroxide Wash in Acne. (1984). InPharma, 441(1), pp.15-15.
Glymed Plus. (2017). GlyMed Plus.
Gloprofessional.com. (2017). glo minerals Makeup & glo therapeutics Skincare | gloProfessional.
mad-skincare. (2017). M.A.D. Skincare.
Panoxyl.com. (2017). PanOxyl | Acne Treatment with Benzoyl Peroxide Formula.
Pcaskin.com. (2017). Skin Care Products.